Isaac Newton Quotes : Sir Isaac Newton was born on January 4, 1643, in Woolsthorpe, England. He was an established physicist and mathematician and is credited as one of the most famous for his law of gravitation, was instrumental in the scientific revolution of the 17th century. He published his most acclaimed work, Philosophiae Naturalis Principia Mathematica (Mathematical Principles of Natural Philosophy), which has been called the single most influential book on physics. Newton died in London on March 31, 1727.